L2 📐 L2-901 ◆ Frontier — not yet benchmarked

Partial-Reprogramming Dose–Response Twin

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Introduction

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Partial-Reprogramming Dose–Response Twin is a digital twin specification derived from principle L1-901. It defines the forward operator and a 3-dimensional parameter space Ω over which benchmarks are seeded. Each benchmark drawn from this twin is a concrete measurement instance with fixed Ω values; solvers must invert that specific measurement.

Derived from L1 L1-901 Epigenetic Reprogramming & Reverse Aging

Ω Parameter Space — 3 dimensions

OSK_dose: 0.0–1.0 cell_type: fibroblast|neuron|hepatocyte induction_days: 1–21
δ = 50 hardness 0.9

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Contents

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On-Chain Artifact Registry

Base Sepolia → Base Mainnet on graduation
L1
L1 Principle L1-901 Testnet
L2
Digital Twin — Partial-Reprogramming Dose–Response Twin L2-901 Testnet

Digital Twin Specification — L2-901

Ω Parameter Space

ParameterRange
OSK_dose 0.0 – 1.0
cell_type fibroblast|neuron|hepatocyte
induction_days 1 – 21

ε (epsilon)

{
  "expression": "\u2264 2 yr error on restored DNAm age, identity markers preserved (no dedifferentiation)",
  "type": "fn"
}
📝 Markdown source — L2-901.md

🎁 Contribute & earn PWM

Improve L2-901 — submit with or without uploading. Accepted submissions earn the 1/16 modify share of A(t).

⬆ Submit by uploading your files earn PWM · unlimited

Upload your .md + .json as a modification of L2-901 — the main way to contribute & earn. Unlimited submissions.

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✨ Or try a free one-click check free · 1×

No files, no typing — we submit a check of L2-901 for you once; it goes through review and earns the 1/16 share. One free no-upload Digital Twin per account.

You'll be asked to log in first — then it's one click, no files.

🛠 Helper: build your files in ChatGPT / Gemini / Claude

Layer template

⬇ spec.md ⬇ spec.json

Fork L2-901

⬇ L2-901.md ⬇ L2-901.json

Prompt — copy into your LLM

You are helping me submit a MODIFICATION of L2-901 (Partial-Reprogramming Dose–Response Twin) to the PWM Protocol — a Digital Twin (L2) artifact.

I will paste a Markdown template (or the current L2-901.md).
1. Rewrite the Markdown so the science is correct and clearly explained for my change.
2. Regenerate the sibling L2-901.json so EVERY field matches the Markdown.
3. Keep the schema in the "File Mapping" footer at the bottom of the MD.
4. Keep the parent reference unchanged unless I ask otherwise.
Rules: the Markdown is the source of truth; use SI units; do NOT invent benchmark scores.
Output each file in its own fenced code block tagged with the filename.

Here is my template:
[PASTE THE .md HERE]